While current guidelines for acute stroke treatment endorse embolectomy when performed within six hours, results from a new trial show that endovascular treatment [ET] is effective in some patients even when performed up to 24 hours after a stroke.
For the trial, stroke patients who arrived at the hospital outside the six-hour time window were randomised to either receive embolectomy or standard medical therapy.
A total of 48.6 per cent of patients receiving ET had a good outcome at 90 days post-treatment, while only 13.1 per cent showed benefit in the group that received standard therapy alone. There was no difference in mortality between the two groups.
The trial was terminated early after it was demonstrated that ET provided significant clinical benefit in the selected patients.
Dr Tudor Jovin, who co-led the trial said while the mantra “time is brain” still holds, “our study shows that even if treated outside the time window, patients will have significantly reduced disability with clot removal.”
The findings were presented this week at the European Stroke Organisation Conference 2017 in Prague.