Higher risk of myocardial infarction in non-O blood types

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Experts suggest blood group should be considered in risk assessment for cardiovascular prevention.

New findings presented at Heart Failure 2017 and the 4th World Congress on Acute Heart Failure at the weekend suggest non-O blood group is associated with higher risk of cardiovascular events.

A meta-analysis of prospective studies of  1,362,569 individuals found having a non-O blood group is associated with a 9 per cent increased risk of both coronary events and combined cardiovascular events. Analysis of fatal coronary events did not show a significant difference between people with O and non-O blood groups.

Lead author Tessa Kole said more research is needed to identify the cause of the apparent increased cardiovascular risk in people with a non-O blood group. She added: “In future, blood group should be considered in risk assessment for cardiovascular prevention, together with cholesterol, age, sex and systolic blood pressure. It could be that people with an A blood group should have a lower treatment threshold for dyslipidaemia or hypertension, for example. We need further studies to validate if the excess cardiovascular risk in non-O blood group carriers may be amenable to treatment.”

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