New findings presented at Heart Failure 2017 and the 4th World Congress on Acute Heart Failure at the weekend suggest non-O blood group is associated with higher risk of cardiovascular events.
A meta-analysis of prospective studies of 1,362,569 individuals found having a non-O blood group is associated with a 9 per cent increased risk of both coronary events and combined cardiovascular events. Analysis of fatal coronary events did not show a significant difference between people with O and non-O blood groups.
Lead author Tessa Kole said more research is needed to identify the cause of the apparent increased cardiovascular risk in people with a non-O blood group. She added: “In future, blood group should be considered in risk assessment for cardiovascular prevention, together with cholesterol, age, sex and systolic blood pressure. It could be that people with an A blood group should have a lower treatment threshold for dyslipidaemia or hypertension, for example. We need further studies to validate if the excess cardiovascular risk in non-O blood group carriers may be amenable to treatment.”