High serum magnesium could reduce fracture risk

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Lower serum magnesium was associated with an increased risk of fracture, particularly fractures of the hip.

Increasing serum magnesium concentrations may protect against future risk of fracture, according to the authors of a new study which explored the association of baseline serum magnesium concentrations with risk of incident fractures.

As part of the study, published in the European Journal of Epidemiology , researchers analysed data on 2,245 men aged 42-61 years in the Kuopio Ischemic Heart Disease prospective cohort study.

They found men with lower levels of magnesium had an increased risk of fracture, particularly fractures of the hip. The risk of having a fracture was reduced by 44 per cent in men with higher magnesium. None of the 22 men who had very high magnesium levels (>2.3mg/dl) experienced a fracture during the follow-up period.

“The findings do suggest that avoiding low serum concentrations of magnesium may be a promising though unproven strategy for risk prevention of fractures,” said Dr. Setor Kunutsor, Research Fellow from the University of Bristol’s Musculoskeletal Research Unit and lead researcher.

The authors said further research is needed to assess the potential relevance of serum magnesium in the prevention of fractures.

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